Further evidence for deletions in 7p14.1 contributing to nonsyndromic cleft lip with or without cleft palate

CONCLUSIONThe present data support the hypothesis that deletions at 7p14 are a common risk factor for nsCL/P. Genome‐wide CNV analyses in nsCL/P cohorts are warranted to explore the functional relevance of these deletions and their contribution to nsCL/P, and to determine exact breakpoints.Birth Defects Research (Part A), 2016.© 2016 Wiley Periodicals, Inc.

Source: Birth Defects Research Part A: Clinical and Molecular Teratology - July 6, 2016 Category: Perinatology & Neonatology Authors: Johanna Klamt, Andrea Hofmann, Anne C. Böhmer, Ann‐Kathrin Hoebel, Lina Gölz, Jessica Becker, Alexander M. Zink, Markus Draaken, Alexander Hemprich, Martin Scheer, Gül Schmidt, Markus Martini, Michael Knapp, Elisabeth Mangold, Franziska Degenhardt, K Tags: Original Research Article Source Type: research