Correlates of Elevated Interleukin-6 and 8-Hydroxy-2′-Deoxyguanosine Levels in Tracheal Aspirates from Very Low Birth Weight Infants Who Develop Bronchopulmonary Dysplasia
Bronchopulmonary dysplasia (BPD) remains the most common complication of very low birth weight (VLBW) preterm infants, and inflammatory regulation plays a role in the development of the BPD. Interleukin-6 (IL-6) has an important role in airway inflammation and therefore can be used as a marker of airway injury. The study aimed to compare the changes between IL-6 and oxidative stress marker with 8-hydroxy-2′-deoxyguanosine (8-OHdG) from serum and tracheal aspiration (TA) in VLBW preterm infants following development of BPD.
Source: Pediatrics and Neonatology - Category: Perinatology & Neonatology Authors: Chien-Chou Hsiao, Jui-Chih Chang, Lon-Yen Tsao, Rei-Cheng Yang, Hsiao-Neng Chen, Cheng-Han Lee, Ching-Yuang Lin, Yi-Giien Tsai Tags: Original article Source Type: research