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Hydroxychloroquine, abatacept linked with reduced type 2 diabetes

LONDON – U.S. rheumatoid arthritis patients had a significantly reduced incidence of type 2 diabetes when on treatment with either hydroxychloroquine or abatacept in an analysis of more than 13,000...
Source: Clinical Endocrinology News - Category: Endocrinology Source Type: news

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CONCLUSION: Chronic exposure to low to medium doses of OGC was associated with significantly increased risk of potential OGC-related AE in patients with RA, and greater cumulative OGC dose was associated with substantially higher AE-related healthcare expenditures among patients with AE. PMID: 29335343 [PubMed - as supplied by publisher]
Source: Journal of Rheumatology - Category: Rheumatology Tags: J Rheumatol Source Type: research
Authors: Gwon SY, Rhee KJ, Sung HJ Abstract The risk of rheumatoid arthritis (RA), an autoimmune disease, in the elderly population increases along with that of atherosclerosis, cardiovascular disease, type 2 diabetes, and Alzheimer's disease. Identifying specific biomarkers for RA can clarify the underlying molecular mechanisms and can aid diagnosis and patient care. To this end, the present study investigated the genes and proteins that are differentially expressed in RA using a mouse collagen-induced arthritis (CIA) model. We performed gene microarray and proteome array analyses using blood samples from the mice...
Source: International Journal of Medical Sciences - Category: Biomedical Science Tags: Int J Med Sci Source Type: research
I’ve heard this advice countless times, as I’ll bet you have, too. I’ve also witnessed many people try it (though certainly not on my advice), only to experience modest (if any) benefits that quickly come a halt. And, of course, this advice makes no sense. “White,” of course, refers primarily to refined grain products such as breads, rolls, and bagels made with white flour, as well as sucrose table sugar. Non-white primarily refers to whole grains that are darker based on the commonly held misconception that whole grains are not just better for you, but healthy. (I’ve discussed this logi...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Wheat Belly Lifestyle gluten-free grain-free grains Inflammation Weight Loss Source Type: blogs
AbstractIntroductionLittle is known about the burden of rheumatoid arthritis (RA) in South Africa. The aim of this study was to establish the prevalence of RA and coexisting chronic disease list (CDL) conditions in the private health sector of South Africa.MethodsA retrospective, cross-sectional analysis was performed on medicine claims data from 1 January 2014 to 31 December 2014 to establish the prevalence of RA. The cohort of RA patients was then divided into those with and those without CDL conditions, to determine the number and type of CDL conditions per patient, stratified by age group and gender.ResultsA total 4352...
Source: Rheumatology International - Category: Rheumatology Source Type: research
Conclusion: People with HIV were more likely to have a poor mental HRQOL than patients with other chronic conditions. Addressing mental health should be an integral part of outpatient HIV care.
Source: AIDS - Category: Infectious Diseases Tags: Epidemiology and Social Source Type: research
Authors: Santangelo C, Vari R, Scazzocchio B, De Sanctis P, Giovannini C, D'Archivio M, Masella R Abstract Altered inflammatory response characterizes chronic immune-mediated inflammatory diseases (IMID) such as rheumatoid arthritis, inflammatory bowel disease, multiple sclerosis, systemic lupus erythematosus, and psoriasis. Accumulating evidence indicates that regular consumption of extra virgin olive oil (EVOO), the main source of fat in the Mediterranean diet, is associated with a reduced risk of developing chronic degenerative disorders such cardiovascular diseases, type 2 diabetes and cancer. The beneficial ef...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Endocr Metab Immune Disord Drug Targets Source Type: research
Conclusions: Older male Veterans with diabetes have a 22% increased risk of incident clinical fracture compared to those without. A significant portion of this risk is explained by diabetes-related comorbidities, specifically peripheral neuropathy and congestive heart failure. Identification of these mediating factors suggests possible mechanisms, as well as potential interventions. PMID: 29099931 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - Category: Endocrinology Authors: Tags: J Clin Endocrinol Metab Source Type: research
Abstract AbstractSeveral studies have pointed out a significant association between rheumatoid arthritis (RA) and accelerated atherosclerosis. At the best of our knowledge, no such study has been carried out in a large Italian series and, in this study, we aimed to investigate the prevalence of both subclinical atherosclerosis and history of cardiovascular events (CVEs), in patients consecutively admitted from January 1, 2015 to December 31, 2015 to Rheumatology Units throughout the whole Italy.Centers members of GIRRCS (Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale) were invited to enrol patients conse...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
"One-tenth of 50-year-old men have a heart age 10 years older than they are," BBC News reports. This is the finding of an analysis of 1.2 million people who used the NHS Heart Age Test. The principle behind the test is that you can "age" your heart through unhealthy behaviour such as smoking and being obese. Underlying conditions like high blood pressure and high cholesterol, which often have no noticeable symptoms, can also age the heart. An obese smoker in their 50s who has high blood pressure and high cholesterol could have the heart of a 60- or 70-year-old. The quick and simple test tells you the...
Source: NHS News Feed - Category: Consumer Health News Tags: Heart/lungs Source Type: news
No abstract available
Source: Medicine - Category: Internal Medicine Tags: Erratum Source Type: research
More News: Abatacept | Arthritis | Diabetes | Diabetes Type 2 | Endocrinology | Hydroxychloroquine | Orencia | Rheumatoid Arthritis | Rheumatology