PI3K/p110{alpha} inhibition selectively interferes with arterial thrombosis and neointima formation, but not re-endothelialization: potential implications for drug-eluting stent design

Conclusion
Following vascular injury, PI3K/p110α inhibition selectively interferes with arterial thrombosis and neointima formation, but not re-endothelialization. Hence, PI3K/p110α represents an attractive new target in DES design.

Source: European Heart Journal - March 21, 2014 Category: Cardiology Authors: Holy, E. W., Jakob, P., Eickner, T., Camici, G. G., Beer, J. H., Akhmedov, A., Sternberg, K., Schmitz, K.-P., Luscher, T. F., Tanner, F. C. Tags: FASTTRACK CLINICAL RESEARCH Source Type: research