Current and Emerging Therapies of Severe Epileptic Encephalopathies

Recent advances in genetics have markedly impacted our understanding of multiple epilepsy syndromes and is expanding our therapeutic options. Epileptic encephalopathies (EEs) comprise a group of clinical entities each with a specific disease course and with electroencephalographic (EEG) abnormalities that cause progressive disturbances of cerebral functions.1 Failure to appropriately recognize an EE in question results in ongoing cognitive and behavioral impairments. EEs are often resistant to conventional antiepileptic drugs (AEDs), hence the interest in new and emerging therapies.
Source: Seminars in Pediatric Neurology - Category: Neurology Authors: Source Type: research