The Role of Nedd4-1 WW Domains in Binding and Regulating Human Organic anion Transporter 1.

In conclusion, this is the first demonstration that Nedd4-1 regulates hOAT1 ubiquitination, expression, and transport activity through its WW2 and WW3 domains.
PMID: 27226107 [PubMed - as supplied by publisher]

Source: Am J Physiol Renal P... - May 24, 2016 Category: Urology & Nephrology Authors: Xu D, Wang H, Gardner CR, Pan Z, Zhang PL, Zhang J, You G Tags: Am J Physiol Renal Physiol Source Type: research