Diabetic nephropathy: Atrasentan stabilizes the endothelial glycocalyx

Nature Reviews Nephrology 12, 315 (2016). doi:10.1038/nrneph.2016.53 Author: Susan J. Allison Endothelin receptor antagonists, such as atrasentan, can reduce albuminuria in patients with diabetic nephropathy. Now, researchers show that atrasentan restores glomerular endothelial glycocalyx coverage. “In the study we not only show that atrasentan restores the glycocalyx in diabetic nephropathy, but also show that this effect
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Tags: Research Highlight Source Type: research