Fluorescent in situ hybridization monitoring and impact of detected early responses in the outcome of CP-CML patients: a report of a Latin American country

Our aim was to assess the routine use of fluorescent in situ hybridization (FISH) in the monitoring of chronic phase chronic myeloid leukemia (CP-CML). We retrospectively analyzed data from 63 patients. The monitoring adherence assessment revealed better compliance rates compared to previous reports. Excellent correlation between FISH and chromosome banding analysis (CBA) was found. Achieving a complete cytogenetic response (CCyR), assessed by FISH, was an independent prognostic factor in the outcome of patients.
Source: Clinical Lymphoma, Myeloma and Leukemia - Category: Hematology Authors: Tags: Original Study Source Type: research