Fluorescent in situ hybridization monitoring and impact of detected early responses in the outcome of CP-CML patients: a report of a Latin American country
Our aim was to assess the routine use of fluorescent in situ hybridization (FISH) in the monitoring of chronic phase chronic myeloid leukemia (CP-CML). We retrospectively analyzed data from 63 patients. The monitoring adherence assessment revealed better compliance rates compared to previous reports. Excellent correlation between FISH and chromosome banding analysis (CBA) was found. Achieving a complete cytogenetic response (CCyR), assessed by FISH, was an independent prognostic factor in the outcome of patients.
Source: Clinical Lymphoma, Myeloma and Leukemia - Category: Hematology Authors: Christianne Bourlon, Carlos Hernandez-Mata, Cesar Vargas-Serafín, María T. Bourlon, Elena Tuna-Aguilar, Alvaro Aguayo Tags: Original Study Source Type: research
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