Metabolic profile of Mycobacterium smegmatis reveals Mce4 proteins are relevant for cell wall lipid homeostasis

Conclusion
These results, together with the finding that the cell surface of the Δmce4 mutant is significantly altered, support a role for Mce4 in maintaining the cell wall lipids architecture of M. smegmatis, which, when altered, induces a redox imbalance that results in the accumulation of the stress-related compounds.

Source: Metabolomics - April 26, 2016 Category: Biology Source Type: research