Characterization and Antihypertensive Effect of the Complex of ( )-β-pinene in β-cyclodextrin.

In conclusion, the slurry complexation method was the best among them. Pharmacological results demonstrated that the complex promoted antihypertensive effect. Furthermore, βP induced endothelium-independent vasorelaxation possibly caused by the inhibition of the Ca2+ influx through L-type Ca2+ channel associated to a decrease in calcium sensitivity.
PMID: 27109904 [PubMed - as supplied by publisher]

Source: Current Pharmaceutical Biotechnology - April 24, 2016 Category: Biotechnology Authors: Moreira ÍJ, Menezes PP, Serafini MR, Araújo AA, Quintans-Júnior LJ, Bonjardim LR, Filho VJ, Júnior DB, Santos SL, Júnior WL, Scotti L, Scotti MT, Santos MR Tags: Curr Pharm Biotechnol Source Type: research