A new biomarker for the early diagnosis of renal damage in obese children; urine netrin-1 level.

CONCLUSION: Urine netrin-1 level could be increased in normotensive and normoalbuminuric obese children before albuminuria. Urinary netrin-1 excretion seemed to be affected predominantly by insulin resistance and hyperinsulinemia. Urine netrin-1 may be a new biomarker for determining early tubular injury in obese children. PMID: 27087488 [PubMed - as supplied by publisher]
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - Category: Endocrinology Tags: J Clin Res Pediatr Endocrinol Source Type: research