Acute and short term chronic testosterone fluctuations effects on glucose homeostasis, insulin sensitivity and adiponectin. A randomized, double-blind, placebo-controlled, cross-over study.

Conclusions: These data show that testosterone can act through putative fast nongenomic pathways to affect adiponectin levels in humans. The early hypogonadal state is characterized by a marked shift in fuel oxidation from lipids towards glucose, which partly may rely on buffering capabilities of adiponectin. PMID: 24606070 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/24606070?dopt=Abstract

Source: The Journal of Clinical Endocrinology and Metabolism - February 28, 2014 Category: Endocrinology Authors: Høst C, Gormsen LC, Hougaard DM, Christiansen JS, Pedersen SB, Gravholt CH Tags: J Clin Endocrinol Metab Source Type: research