Endothelial fibrinolytic response onto an evolving matrix of fibrin

Conclusions HMEC-1 cells influence fibrin formation and dissolution as a function of the fibrin content of clots. Clot degradation was accentuated at high fibrin concentrations. The secretion of fibrinolytic components by HMEC-1 cells seemed to be modulated by integrins that bind RGD ligands.
Source: BMC Hematology - Category: Hematology Source Type: research