Morning Home Blood Pressure Is a Strong Predictor of Coronary Artery Disease The HONEST Study

BackgroundFew studies have evaluated out-of-office blood pressure (BP) measurements as predictors of coronary artery disease (CAD) events.ObjectivesThe aim of this study was to determine morning home blood pressure (HBP) as a predictor of CAD events.MethodsUsing data from the HONEST (Home blood pressure measurement with Olmesartan Naive patients to Establish Standard Target blood pressure) study, we investigated the relationship between morning HBP and incidence of stroke and CAD events.ResultsIn 21,591 treated hypertensive patients (mean age 64.9 years; mean follow-up 2.02 years), 127 stroke events (2.92 per 1,000 patient-years), and 121 CAD events (2.78 per 1,000 patient-years) occurred. The incidence of stroke events was significantly higher in patients with morning home systolic blood pressure (HSBP) ≥145 mm Hg compared with 

Source: Journal of the American College of Cardiology - March 29, 2016 Category: Cardiology Source Type: research