Pd07-08 changes in testicular volume and function after testosterone replacement vs. restoration: analysis of a randomized, double blind, placebo-controlled trial of enclomiphene citrate vs. androgel™ 1.62% in men with secondary hypogonadism

Testicular volume (TV) loss and impaired spermatogenesis are frequently observed after exogenous testosterone (T) replacement. For that reason, selective estrogen receptor modulators (SERM) are used to treat hypogonadal infertile men. The TV changes with SERM or exogenous T replacement have not been prospectively studied. Our objective was to investigate changes in testicular volume, male hormones and seminal parameters in men receiving testosterone gel (Androgel 1.62%, AG) vs. a novel SERM (Enclomiphene citrate, EC) vs.
Source: The Journal of Urology - Category: Urology & Nephrology Authors: Tags: Infertility: Therapy II Source Type: research