A new perspective of the structural complexity of HCMV-specific T-cell responses

Conclusions Predicting protective immunity based on isolated HCMV subunit-specific T-cell responses is questionable in light of the complex architecture of the overall response. Our findings have important implications for T-cell monitoring, intervention strategies, as well as the application of animal models to the understanding of human infection.
Source: Mechanisms of Ageing and Development - Category: Geriatrics Source Type: research