The SNP rs1625579 in miR-137 gene and risk of schizophrenia in Chinese population: a meta-analysis

Schizophrenia is a severe psychiatric disorder with a high heritability. A single nucleotide polymorphism (SNP) rs1625579 (G/T; T is the common and presumed risk allele) within an intron of miR-137 gene has been recently suggested to contribute to the susceptibility to schizophrenia by a large-scale genome-wide association study (GWAS) in a sample of predominantly European ancestry. However, subsequent genetic association studies in Chinese population yielded inconsistent results.

Source: Comprehensive Psychiatry - February 12, 2016 Category: Psychiatry Authors: Ping Zhang, Yi Bian, Na Liu, Yingxin Tang, Chao Pan, Yang Hu, Zhouping Tang Source Type: research