Divergent Outcomes in Cognitive-Behavioral Therapy and Pharmacotherapy for Adult Depression.

CONCLUSIONS: Deterioration and extreme nonresponse and, similarly, superior improvement and superior response, both occur infrequently in randomized clinical trials comparing CBT and pharmacotherapy for depression. Pretreatment symptom levels help forecast negative and unusually positive outcomes but do not guide selection of CBT versus pharmacotherapy. Pharmacotherapy may produce clinician-rated superior improvement and attrition more frequently than does CBT. PMID: 26869246 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/26869246?dopt=Abstract

Source: The American Journal of Psychiatry - February 12, 2016 Category: Psychiatry Authors: Vittengl JR, Jarrett RB, Weitz E, Hollon SD, Twisk J, Cristea I, David D, DeRubeis RJ, Dimidjian S, Dunlop BW, Faramarzi M, Hegerl U, Kennedy SH, Kheirkhah F, Mergl R, Miranda J, Mohr DC, Rush AJ, Segal ZV, Siddique J, Simons AD, Cuijpers P Tags: Am J Psychiatry Source Type: research

More News: Clinical Trials | Depression | Psychiatry