Basic research: TMEM107: a new ciliopathy transition zone gene

Nature Reviews Nephrology 12, 62 (2016). doi:10.1038/nrneph.2015.212 Author: Jessica K. Edwards A bioinformatics-based analysis has identified TMEM107 as a candidate transition zone (TZ) ciliary gene that is mutated in oral–facial–digital and Joubert syndromes. Functional analyses performed in C. elegans showed that TMEM107 contributes to ciliary composition and function in a redundant manner with NPHP-4,
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Tags: Research Highlight Source Type: research