Exploring Epigenomic or Non-Coding RNA Regulation in HIV/AIDS and Substance Abuse (R01)

Funding Opportunity RFA-DA-16-012 from the NIH Guide for Grants and Contracts. The goal of this Funding Opportunity Announcement (FOA) is to stimulate innovative hypothesis-driven research to enhance our understanding of the role of epigenomic or non-coding RNA regulatory mechanisms in HIV/AIDS infection or disease trajectory in combination with substance use or abuse. We are particularly interested in understanding regulatory mechanisms that influence selection and regulation of HIV sites of integration in the host genome. A deeper understanding of these mechanisms could lead to novel approaches for monitoring latent HIV in cellular reservoirs, especially in the central nervous system. Ultimately, research in this area could enable the identification of molecular targets that could be manipulated either to eliminate or permanently repress HIV in cellular reservoirs.
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding