Review examines the extent of antimicrobial resistance in bacteria from horses
(Wiley) Bacterial resistance to antimicrobial agents is a significant problem for both human and veterinary medicine, but little research has been done on the prevalence or mechanisms of resistance in horses and other companion animals, and how such resistance might impact human health.
Publication date: Available online 21 July 2019Source: Veterinary MicrobiologyAuthor(s): Clémence Bourély, Géraldine Cazeau, Eric Jouy, Marisa Haenni, Jean-Yves Madec, Nathalie Jarrige, Agnès Leblond, Emilie GayAbstractSurveillance of Pasteurella multocida resistance in food-producing animals is essential to guide the first-line treatment of respiratory diseases and to limit economic losses. Since Pasteurella are the most common bacteria isolated from dog and cat bites, this surveillance is also needed to guide treatment in humans in case of bites. The aim of this study was to characterize the p...
ConclusionsWe think that the most appropriate antibiotic to be chosen for the outpatients for empirical treatment in all age groups in our region, is as oral nitrofurantoin and parenteral amikacin. Also the appropriate parenteral antibiotics that should be selected for the empirical treatment of inpatients UTI in all age groups are the TZP, amikacin and carbapenems.
ConclusionsST10 is considered a high-risk clone worldwide. This type of mcr-1-harboring clone is a major concern for human and animal health and must be under close surveillance.In this work we detected the presence of mcr-1 for the first time in our country, albeit in an allodemic manner, associated with different antibiotic resistance genes and from diverse clinical contexts.Considering that colistin is often the last therapeutic option available for multidrug-resistant Gram-Negative Bacilli infections, it is necessary to maximize precautions to avoid the dissemination of isolates carrying mcr-1.
ConclusionsThis investigation of the susceptibility of a range of LA-, HA- and CA-MRSA strains using standardized conditions gave no indication that LA-MRSA strains are less susceptible to commonly used antiseptics compared to HA- and CA-MRSA strains.
ConclusionsWe identified distinct seasonal variation in detection of respiratory viruses and bacterial pathogens.C. difficile seasonality may, in part, be related to antibiotic prescriptions filled; GNB seasonality may be related to ambient temperature andS. pneumoniae may be related to concurrent respiratory viral infections.
ConclusionsOur findings show that almost 42% PIVCs resulted in unplanned removal, amplifying the importance in terms of morbidity, mortality and patient safety. A high number of positive tip cultures without clinical signs and symptoms was observed. We underpin the importance to remove unnecessary PIVCs for the prevention of CRBSI.
ConclusionsAlthough both German and Dutch HCW are aware of the AMR problem, they should be more empowered to contribute to limiting AMR through APM (i.e. screening diagnostics, infection diagnosis, treatment and infection control) in their daily working routines. The observed differences reflect differences in local, national and cross-border structures, and differences in needs of HCW, that need to be considered for safe patient exchange and effective cross-border APM.
Authors: Caselli E, D'Accolti M, Soffritti I, Lanzoni L, Bisi M, Volta A, Berloco F, Mazzacane S Abstract Antimicrobial resistance (AMR) is currently one of the main concerns for human health.Due to its rapid increase and global diffusion, several common microbial infections might become not curable in the future decades, making it impossible to apply other lifesaver therapies, such as transplant or chemotherapy.AMR is frequently observed in hospital pathogens, due to selective pressure exerted by antibiotic use, and consistently with this, in the recent years, many actions have been proposed to limit AMR spread, i...
;s JM Abstract SUMMARYThe genus Enterobacter is a member of the ESKAPE group, which contains the major resistant bacterial pathogens. First described in 1960, this group member has proven to be more complex as a result of the exponential evolution of phenotypic and genotypic methods. Today, 22 species belong to the Enterobacter genus. These species are described in the environment and have been reported as opportunistic pathogens in plants, animals, and humans. The pathogenicity/virulence of this bacterium remains rather unclear due to the limited amount of work performed to date in this field. In contrast, its re...
ConclusionsOur findings confirmed that in INSTI-naïve patients, major INSTI-RMs occur very rarely. Under INSTI treatment, selection of drug-resistance follows the typical drug-resistance pathways; a higher evolution characterizes integrase sequences developing drug-resistance compared to those without any resistance.