Depression Common in Patients Awaiting Lung TransplantDepression Common in Patients Awaiting Lung Transplant
More than half of patients waiting for a lung transplant suffered from psychologic stress in a new study, which might be serious enough to affect transplant outcomes. Medscape Medical News
Transplant International,Volume 31, Issue 5, Page 481-483, May 2018.
This study demonstrates that small peptide domains derived from native protein amelogenin can be utilized to construct a mineral layer on damaged human enamel in vitro. Six groups were prepared to carry out remineralization on artificially created lesions on enamel: (1) no treatment, (2) Ca2+ and PO43- only, (3) 1100 ppm fluoride (F), (4) 20 000 ppm F, (5) 1100 ppm F and peptide, and (6) peptide alone. While the 1100 ppm F sample (indicative of common F content of toothpaste for homecare) did not deliver F to the thinly deposited mineral layer, high F test sample (indicative of clinical varnish treatment) formed mainly C...
In the context of limited donor pool in cardiothoracic transplantation, utilization of organs from high risk donors, such as suicidal hanging donors, while ensuring safety, is under consideration. We sought to evaluate the outcomes of lung transplantations (LTx) that use organs from this group. Between January 2011 and December 2015, 265 LTx were performed at our center. Twenty-two recipients received lungs from donors after suicidal hanging (group 1). The remaining 243 transplantations were used as a control (group 2). Analysis of recipient and donor characteristics as well as outcomes was performed. No statistically si...
Use of CF-LVADs is established therapy for advanced HF. Psychosocial factors affect pt. outcomes; however, only recently have objective tools been developed to evaluate psychosocial risk. The mPACT is a tool for assessing this risk in LVAD candidates by assessing social support, psychological health, lifestyle and ability to understand care. The purpose of this study was to further evaluate validity and reliability of mPACT. We aimed to describe (1) clinical and psychosocial risks of candidates and (2) determine relationships among attributes of mPACT and relevant individual characteristics (e.g., physical activity, resili...
We examined variability in depressive symptoms internationally, and explored multilevel correlates from a patient-, family/healthcare provider-, healthcare organization-, and healthcare system perspective.
Patients with advanced heart failure commonly experience severe physical symptoms along with depression. The purpose of this study was to determine if changes in physical symptoms and depression occur in a similar fashion among adults undergoing left ventricular assist device (LVAD) implantation.
Depression may affect clinical outcomes after HTx, but most studies have examined only short periods (averaging 5 years) of follow-up. We sought to examine whether depression after HTx is associated with impaired survival during long-term follow-up.
Prior studies have reported depression among patients post-left ventricular assist device (LVAD) implant. We expand upon this knowledge by reporting the degree of depressive symptoms in community-dwelling LVAD patients and associations with age, gender and marriage status.
We examined relationships between PHQ-9 scores and quality of life (QOL) of VAD patients at repeated intervals utilizing the Patient Visual Analog Status (VAS).
Extracorporeal Membrane Oxygenation (ECMO) is increasingly used as a bridge to lung transplantation. The impact of preoperative ECMO on health-related quality of life (HRQL) and depressive symptoms after lung transplant, however, remains unknown.