Comparison of the Genomic Landscape Between Primary Breast Cancer in African American Versus White Women and the Association of Racial Differences With Tumor Recurrence [Breast Cancer]

Conclusion African Americans had greater intratumor genetic heterogeneity and more basal gene expression tumors, even within triple-negative breast cancer. This pattern suggests more aggressive tumor biology in African Americans than whites, which could contribute to racial disparity in breast cancer outcome.

http://jco.ascopubs.org/cgi/content/short/33/31/3621?rss=1

Source: Journal of Clinical Oncology - October 29, 2015 Category: Cancer & Oncology Authors: Keenan, Moy, Mroz, Ross, Niemierko, Rocco, Isakoff, Ellisen, Bardia Tags: Epidemiology Breast Cancer Source Type: research