Emergency care outcomes of acute chemical poisoning cases in Rawalpindi

Conclusions Findings suggest that controlling access of poisonous substances in youth and at homes might reduce related ED care burden. Safety promotion agencies and emergency physicians can use these findings to develop safety messages.
Source: Journal of Acute Disease - Category: Emergency Medicine Source Type: research

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This study aims to analyze the splicing characteristics of dystrophin PEs and compare them with those of dystrophin canonical exons (CEs). Forty-two reported dystrophin PEs were divided into a splice site (ss) group and a splicing regulatory element (SRE) group. Five dystrophin PEs with characteristics of poison exons were identified and categorized as the possible poison exon group. The comparative analysis of each essential splicing signal among different groups of dystrophin PEs and dystrophin CEs revealed that the possible poison exon group had a stronger 3′ ss compared to any other group. As for auxiliary SR...
Source: Genes - Category: Genetics & Stem Cells Authors: Tags: Article Source Type: research
Publication date: Available online 8 October 2020Source: Journal of Clinical and Experimental HepatologyAuthor(s): Ravi Mohanka, Prashantha Rao, Mitul Shah, Amit Gupte, Vinayak Nikam, Mihir Vohra, Ruhi Kohli, Anurag Shrimal, Ankush Golhar, Ameya Panchwagh, Saurabh Kamath, Akash Shukla, Priyesh Patel, Somnath Chattopadhyay, Gaurav Chaubal, Yasmin Shaikh, Vidhi Dedhia, Shivali S. Sarmalkar, Ravikiran Maghade, Kavita Shinde
Source: Journal of Clinical and Experimental Hepatology - Category: Gastroenterology Source Type: research
Conclusion: The incidence of visual dysfunction in patients with CO poisoning was high, the clinical symptoms were rich and diverse, the duration of disease was long, and the prognosis was poor. Thus, the relevant ophthalmological examination and intervention treatment should be perfected as soon as possible. PMID: 33029389 [PubMed]
Source: Journal of Ophthalmology - Category: Opthalmology Tags: J Ophthalmol Source Type: research
CONCLUSIONS: The majority of studies on drug poisoning deaths among women involved descriptive epidemiological data, primarily prevalence estimates, with limited in-depth analyses of factors explaining these trends. To inform policies and practices to prevent drug poisoning deaths among women, more evidence is required on risk factors specifically related to women. PMID: 33028464 [PubMed - in process]
Source: Journal of Studies on Alcohol and Drugs - Category: Addiction Tags: J Stud Alcohol Drugs Source Type: research
Black children and children living in urban areas are less likely to have opioid-related poisoning or withdrawal but more likely to experience abuse or dependence, according to a study.Medscape Medical News
Source: Medscape Psychiatry Headlines - Category: Psychiatry Tags: Psychiatry News Source Type: news
Authors: Cheng X, Wang G, Liao Y, Mo J, Qing C Abstract 13-Chlorine-3,15-dioxy-gibberellic acid methyl ester (GA-13315) is a gibberellin derivative that exhibits selective cytotoxicity to multidrug resistant MCF-7/ADR cells and reverses drug resistance when administered at subtoxic doses in combination with chemotherapy drugs. The present study aimed to investigate the impact of chronic GA-13315 exposure on the chemosensitivity of MCF-7 and HCT116 cell lines. Cells were administered a subtoxic dose of 1 µM GA-13315 for 12 weeks and the sensitivity of the cells to GA-13315, irinotecan and cisplatin, was assess...
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
Publication date: Available online 5 October 2020Source: Environmental Toxicology and PharmacologyAuthor(s): Thilini Madushanka Wijerathna, Fahim Mohamed, Indika Bandara Gawarammana, Klintean Wunnapuk, Dhammika Menike Dissanayake, Fathima Shihana, Nicholas Alan Buckley
Source: Environmental Toxicology and Pharmacology - Category: Environmental Health Source Type: research
The findings counter claims that wearing face masks to prevent spread of the new coronavirus may put some people's health at risk.
Source: WebMD Health - Category: Consumer Health News Source Type: news
Authors: Elahi S, Fujikawa H Abstract Staphylococcus aureus food poisoning is caused by the intoxication of staphylococcal enterotoxin (SE) produced in foods. Staphylococcal food poisoning is mostly due to staphylococcal enterotoxin type A (SEA) among SEs. There have been many studies on the growth and SEA production of S. aureus in various foods, but few studies in bread. Thus, the SEA production by S. aureus in dough during fermentation and the SEA inactivation in dough during baking were studied in the normal production processes of bread in this study. No growth of S. aureus or SEA production in dough, whose to...
Source: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan - Category: Food Science Tags: Shokuhin Eiseigaku Zasshi Source Type: research
Authors: Ishizaki N, Kamata Y, Furuhata K, Sugita-Konishi Y Abstract Staphylococcal food poisoning (SFP) is caused by Staphylococcus aureus, and its typical symptom of vomiting is evoked by staphylococcal enterotoxins (SEs). SEs are classified as classical and new types. SEQ is a new-type enterotoxin predicted to have a high potential risk for SFP. To elucidate the correlation between the number of S. aureus cells and the production of SEs as well as classical and new-type enterotoxins in the food environment, the numbers of S. aureus strain cells carrying sea and seq genes and the production of SEA and SEQ protein...
Source: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan - Category: Food Science Tags: Shokuhin Eiseigaku Zasshi Source Type: research
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