Exploring the genetics of irritable bowel syndrome: a GWA study in the general population and replication in multinational case-control cohorts

Conclusions
Our results demonstrate that general population-based studies combined with analyses of patient cohorts provide good opportunities for gene discovery in IBS. The 7p22.1 and other risk signals detected in this study constitute a good starting platform for hypothesis testing in future functional investigations.

Source: Gut - October 8, 2015 Category: Gastroenterology Authors: Ek, W. E., Reznichenko, A., Ripke, S., Niesler, B., Zucchelli, M., Rivera, N. V., Schmidt, P. T., Pedersen, N. L., Magnusson, P., Talley, N. J., Holliday, E. G., Houghton, L., Gazouli, M., Karamanolis, G., Rappold, G., Burwinkel, B., Surowy, H., Rafter, J Tags: Irritable bowel syndrome Neurogastroenterology Source Type: research