Aliskiren in early postnatal life prevents hypertension and reduces asymmetric dimethylarginine in offspring exposed to maternal caloric restriction

Conclusions: Early aliskiren therapy prevents CR-induced hypertension via ADMA reduction, decreases angiotensinogen expression, and increases renal angiotensin II type 2 receptor and Mas protein.

http://jra.sagepub.com/cgi/content/abstract/16/3/506?rss=1

Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - September 7, 2015 Category: Biomedical Science Authors: Hsu, C.-N., Lee, C.-T., Huang, L.-T., Tain, Y.-L. Tags: Original Articles Source Type: research