A chemotaxonomic study of phytochemicals in Hedyotis corymbosa

Publication date: October 2015 Source:Biochemical Systematics and Ecology, Volume 62 Author(s): Hongquan Li, Chun Li, Bohou Xia, Yamin Zhou, Limei Lin, Duanfang Liao An investigation of Hedyotis corymbosa resulted in the isolation of eighteen compounds, including six iridoids (1–6), six monocyclic phenols (7–12), one triterpene (13), two sterols (14–15), one anthranquinone (16), one oxylipin (17) and one coumarin (18). The compounds were identified as scandoside methyl ester (1), deacetyl asperulosidic acid (2), deacetyl asperulosidic acid methyl ester (3), daphylloside (4), 10-O-benzoyl deacetyl asperulosidic acid methyl ester (5), 10-O-benzoyl scandoside methyl ester (6), p-hydroxybenzaldehyde (7), 4-methoxybenzene-1,2-diol (8), Z-p-hydroxyphenylacetyl (9), p-hydroxybenzoic acid (10), E-p-hydroxyphenylacetyl (11), protocatechuic acid (12), oleanic acid (13), daucosterol (14), β-sitosterol (15), 1-methoxy-2-hydroxyanthraquinone (16), (9R*,10S*,7E)-6,9,10-trihydroxyocta- dec-7-enoic acid (17) and hedyotiscone A (18). Compounds 4, 7–9, 11 and 17 were isolated from H. corymbosa for the first time, compound 8 was a new natural product. The chemotaxonomic significance of these compounds was summarized in the paper. The presence of (9R*,10S*,7E)-6,9,10-trihydroxyoctadec-7-enoic acid (17) in H. corymbosa could be used to differentiate it from Hedyotis diffusa. Compounds with a 10-O-benzoyl structure, such as compounds 5 and 6, could be used as typical compo...

Source: Biochemical Systematics and Ecology - September 4, 2015 Category: Biochemistry Source Type: research