Vest study results

I've heard that there was a study done comparing the vest therapy to PEP and apparently PEP came out on top. Anyone have more details on that?
Source: Cystic Fibrosis Airway Clearance Techniques Forum - Category: Respiratory Medicine Authors: Tags: Airway Clearance Techniques Source Type: forums

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Notice NOT-DK-19-023 from the NIH Guide for Grants and Contracts
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding
Conditions:   Cystic Fibrosis;   Nontuberculous Mycobacterium Infection Intervention:   Other: Epidemiologic investigation Sponsors:   National Jewish Health;   Cystic Fibrosis Foundation Recruiting
Source: - Category: Research Source Type: clinical trials
Source: ScienceNOW - Category: Science Authors: Tags: Medicine, Diseases perspective Source Type: news
Source: ScienceNOW - Category: Science Authors: Tags: twis Source Type: news
We examined the safety and efficacy of aerosolized xylitol use for 2  weeks in subjects hospitalized with a pulmonary exacerbation of CF.
Source: Journal of Cystic Fibrosis - Category: Respiratory Medicine Authors: Tags: Original Article Source Type: research
Introduction Non-cystic fibrosis (CF) bronchiectasis ("bronchiectasis") is a chronic airway disease for which little data exist to inform treatment decisions. We sought to compare the risks of respiratory infections in chronic users of inhaled corticosteroids (ICSs) versus macrolide monotherapy. Methods We identified a cohort of US Medicare enrollees with a bronchiectasis diagnosis (International Classification of Diseases, Ninth Revision, Clinical Modification code 494.0 or 494.1) between 2006 and 2014, excluding CF. We defined chronic new use as the first ≥28-day prescription of ICS therapy or macrolide mon...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: CF and non-CF bronchiectasis Original Articles: Bronchiectasis Source Type: research
Pseudomonas aeruginosa is the most prevalent opportunistic pathogen in the airways of cystic fibrosis (CF) patients. The pulmonary disorder is characterized by recurrent microbial infections and an exaggerated host inflammatory immune response led primarily by influx of neutrophils. Under these conditions, chronic colonization with P. aeruginosa is associated with diminished pulmonary function and increased morbidity and mortality. P. aeruginosa has a wide array of genetic mechanisms that facilitate its persistent colonization of the airway despite extensive innate host immune responses. Loss of function mutations in the q...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Dysfunction of the pancreas is related to a number of diseases, most famously diabetes. Conditions such as cystic fibrosis-related diabetes (CFRD), are particularly difficult to study in a laboratory setting, but researchers at Cincinnati Children&rs...
Source: Medgadget - Category: Medical Devices Authors: Tags: Materials Medicine Source Type: blogs
The last decade has witnessed developments in the CF drug pipeline which are both exciting and unprecedented, bringing with them previously unconsidered challenges. The Task Force group came together to consider these challenges and possible strategies to address them. Over the last 18  months, we have discussed internally and gathered views from a broad range of individuals representing patient organizations, clinical and research teams, the pharmaceutical industry and regulatory agencies. In this and the accompanying article, we discuss two main areas of focus: i) optimising t rial design and delivery for speed/efficie...
Source: Journal of Cystic Fibrosis - Category: Respiratory Medicine Authors: Tags: Review Source Type: research
Conclusions Cystic fibrosis or CFTR-RD can present as ARP/CP. Complete diagnostic testing for CFTR-RD in patients with ARP/CP will broaden treatment options and help to identify comorbid illness.
Source: Pancreas - Category: Gastroenterology Tags: Original Articles Source Type: research
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