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Recent research has shown that obesity and inactivity is actually the second leading cause of preventable death in the United States. About 400,000 Americans die each year from this cause, compared to 435,000 from the leading cause—tobacco use.
Source: Cystic Fibrosis Exercise and Fitness Forum - Category: Respiratory Medicine Authors: Tags: Exercise & Fitness Source Type: forums

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Gastro-oesophageal reflux disease (GORD) and obesity are associated with frequent exacerbations and poor quality of life in people living with asthma. Multiple mechanisms have been proposed for the effect of obesity, including modification of inflammation affecting epithelial cell proliferation and wound repair, while the role of GORD is poorly understood and proton pump inhibitors (PPIs) are of variable efficacy. GORD might exert a deleterious effect by inducing vagal reflex, neuroinflammation and directly triggering airway inflammation (via microaspiration). Studies of reflux in animal models and human bronchial epitheli...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Original Articles: Research letters Source Type: research
Source: Journal of Cystic Fibrosis - Category: Respiratory Medicine Authors: Tags: Posters Sessions Source Type: research
Authors: Colombo C, Nobili RM, Alicandro G Abstract INTRODUCTION: Optimizing nutrition remains the cornerstone of therapy for patients with cystic fibrosis (CF) since it is associated with better pulmonary function and survival. However, a significant proportion of patients still fail to achieve normal growth and nutritional status. Areas covered. This review describes the current challenges in providing effective nutritional therapy in CF with a focus on the current issues related to energy imbalance, dietary composition, adherence to nutritional recommendations, pancreatic enzyme replacement therapy, and the effe...
Source: Expert Review of Respiratory Medicine - Category: Respiratory Medicine Tags: Expert Rev Respir Med Source Type: research
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
Conclusion Microorganisms are involved in many life activities, and affect their surrounding environment and other organisms. Microorganisms play important roles in human heath, crop growth, livestock farming, environmental management, industrial chemical production and food production. In the 19th century, people first observed microbes using microscopes and began to study them. However, the development of high-throughput sequencing technology has led to generation of large amounts of microbial related data. As a result, machine-learning methods are now being applied to microbiological research. Here, we discuss the curr...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Smith Etareri Evivie1,2†, Amro Abdelazez1,3, Bailiang Li1†, Xin Bian4, Wan Li1, Jincheng Du1, Guicheng Huo1* and Fei Liu1 1Key Laboratory of Dairy Science, Ministry of Education, College of Food Sciences, Northeast Agricultural University, Harbin, China 2Food Science and Nutrition Unit, Department of Animal Science, Faculty of Agriculture, University of Benin, Benin City, Nigeria 3Department of Dairy Microbiology, Animal Production Research Institute, Agriculture Research Center, Giza, Egypt 4Department of Food Engineering, Harbin University of Commerce, Harbin, China Foodborne pathogens are a ma...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Conclusions: Asthma was associated to bronchiectasis in 76% of the patients but it was estimated as etiology in only every fifth patient. However, retrospectively it is difficult to exclude asthma as a background cause in many cases with recurrent asthma like symptoms and respiratory infections. Nevertheless, in one fifth of the patients no identifiable cause was found. None of the patients had had tuberculosis. Lung function test results were well preserved and in 66% bronchiectasis was restricted to one-three lobes.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Epidemiology Source Type: research
Background: Although progress has been made in the standardized interpretation of nocturnal oximetry in children with obstructive sleep-disordered breathing (SDB), no evidence exists on how to score oximetry in other respiratory disorders.Aims: To compare measures of nocturnal oxyhemoglobin desaturation in obstructive lung disease (OLD: cystic fibrosis; obliterative bronchiolitis; bronchopulmonary dysplasia) and SDB.Methods: Nocturnal oximetry was performed in children aged>1 yr with: (i) OLD; (ii) snoring and adenotonsillar hypertrophy and/or obesity; and (iii) no respiratory disorder (controls). Outcomes were: (i) oxy...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Paediatric respiratory physiology and sleep Source Type: research
Conclusion: In childhood age group, pulmonary emboli should be considered as a differential diagnosis of acute chest pain and diagnostic examinations should be planned.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Paediatric bronchology Source Type: research
Purpose of review To summarize recent developments the role of vitamin D and treatment of vitamin D deficiency in cystic fibrosis. Recent findings Although treatment of low vitamin D levels continues to be important for optimizing bone health in cystic fibrosis, increasing data on the extraskeletal effects of vitamin D are becoming available. Exploratory studies of vitamin D in modulation of respiratory and intestinal microbiomes, and the influence of vitamin D on the metabolomic signature of cystic fibrosis, suggest expanded roles for vitamin D in cystic fibrosis disease and treatment. Summary Emerging development...
Source: Current Opinion in Endocrinology, Diabetes and Obesity - Category: Endocrinology Tags: PARATHYROIDS, BONE AND MINERAL METABOLISM: Edited by Vin Tangpricha Source Type: research
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