Early treatment with atorvastatin exerts parenchymal and vascular protective effects in experimental cerebral ischemia

CONCLUSIONS AND IMPLICATIONSAcute atorvastatin provides global cerebral protection, but only at the higher dose of 20 mg/kg/d, related to a reduction of inflammation in both vascular and parenchymal compartments. Our results suggest that atorvastatin could also be beneficial when administered early after stroke.

Source: British Journal of Pharmacology - August 19, 2015 Category: Drugs & Pharmacology Authors: C Potey, T Ouk, O Petrault, M Petrault, V Berezowski, J Salleron, R Bordet, S Gautier Tags: RESEARCH PAPER Source Type: research