Adaptation requirements due to anatomical changes in free-breathing and deep-inspiration breath-hold for standard and dose-escalated radiotherapy of lung cancer patients.

CONCLUSION: Phantom simulations provided potential adaptation action levels for PE and TS. For the more complex patient geometry, individual assessment of the dosimetric impact is recommended for both ST and DE plans in DIBH as well as in FB. However, DIBH was found to be superior over FB for DE plans, regarding robustness of <D>GTV-T to TS.
PMID: 26206518 [PubMed - as supplied by publisher]

Source: Acta Oncologica - July 24, 2015 Category: Cancer & Oncology Authors: Sibolt P, Ottosson W, Sjöström D, Larsen C, Behrens CF Tags: Acta Oncol Source Type: research