Modulation of cortical motor evoked potential after stroke during electrical stimulation of the lateral cerebellar nucleus

Deep brain stimulation (DBS) targeting the dentato-thalamo-cortical (DTC) pathway at its origin in the lateral cerebellar nucleus (LCN) has been shown to enhance motor recovery in a rodent model of cortical ischemia. LCN DBS also yielded frequency specific changes in motor cortex excitability in the normal brain, indexed by motor evoked potential (MEP) amplitude.

Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - July 8, 2015 Category: Neurology Authors: Hyun-Joo Park, Havan Furmaga, Jessica Cooperrider, John T. Gale, Kenneth B. Baker, Andre G. Machado Source Type: research