Asymmetric synthesis of atropisomeric arylpyrazoles via direct arylation of 5-aminopyrazoles with naphthoquinones

Org. Biomol. Chem., 2024, Accepted Manuscript DOI: 10.1039/D4OB00514G, CommunicationJiamin Liu, Xingfu Wei, Yue Wang, Jingping Qu, Baomin Wang Construction of axially chiral arylpyrazoles represents an attractive challenge due to the relatively low rotational barrier of biaryl structures containing five-membered heterocycles. This work described the catalytic asymmetric construction of... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research