Gonadotropin elevation is ootoxic to ovulatory oocytes and inhibits oocyte maturation, and activin decoy receptor ActRIIB:Fc therapeutically restores maturation

Elevated FSH often occurs in women of advanced maternal age (AMA, age  ≥ 35) and in infertility patients undergoing controlled ovarian stimulation (COS). There is controversy on whether high endogenous FSH cont...

Source: Reproductive Biology and Endocrinology - May 6, 2024 Category: Endocrinology Authors: Lori R. Bernstein, Amelia C. L. Mackenzie, Charles L. Chaffin, Se-Jin Lee, Duane C. Kraemer and Istvan Merchenthaler Tags: Research Source Type: research