CircHIF1A induces cetuximab resistance in colorectal cancer by promoting HIF1 α-mediated glycometabolism alteration

Epidermal growth factor receptor (EGFR)-targeted therapy is an important treatment for RAS wild-type metastatic colorectal cancer (mCRC), but the resistance mechanism remains unclear. Here, the differential ex...

Source: Biology Direct - May 7, 2024 Category: Biology Authors: Yiting Geng, Xiao Zheng, Dachuan Zhang, Shanshan Wei, Jun Feng, Wei Wang, Luo Zhang, Changping Wu and Wenwei Hu Tags: Research Source Type: research