Autoantibodies against complement proteins in patients with antiphospholipid syndrome: Prevalence and clinical associations

Eur J Immunol. 2024 May 3:e2350832. doi: 10.1002/eji.202350832. Online ahead of print.ABSTRACTSeventy-seven patients with antiphospholipid syndrome were tested for autoantibodies against C1q, C3, FB, FH, and C4bp. Fifty-seven patients had at least one anti-complement antibody. IgM anti-FH positivity was associated with thrombosis when anti-C3 and anti-FB were, negatively or positively, associated with various noncriteria manifestations of antiphospholipid syndrome.PMID:38700064 | DOI:10.1002/eji.202350832

Source: European Journal of Immunology - May 3, 2024 Category: Allergy & Immunology Authors: R émi Philip Achille Aouba Nicolas Martin Silva Delphine Mariotte Houcine Hamidi Sanae Rhouni Luc Darnige Marie-Agn ès Dragon-Durey Source Type: research