Generation of ‘semi-guided’ cortical organoids with complex neural oscillations

Nature Protocols, Published online: 03 May 2024; doi:10.1038/s41596-024-00994-0This protocol details the generation of cortical organoids with complex neural oscillations through a ‘semi-guided’ protocol, and their functional characterization using microelectrode array measurements, calcium imaging and adeno-associated virus transduction.

Source: Nature Protocols - May 3, 2024 Category: Biomedical Science Authors: Michael Q. Fitzgerald Tiffany Chu Francesca Puppo Rebeca Blanch Miguel Chill ón Shankar Subramaniam Alysson R. Muotri Source Type: research