Effect of opicapone and entacapone on early morning-OFF pattern in Parkinson ’s disease patients with motor fluctuations

Background: Opicapone (OPC), a once-daily catechol-O-methyltransferase inhibitor, was shown to be effective for end-of-dose motor fluctuations in Parkinson ’s disease patients in two large multinational trials (BIPARK-I and II).

Source: Parkinsonism and Related Disorders - May 1, 2024 Category: Neurology Authors: A. Videnovic, W. Poewe, A. Lees, J.J. Ferreira, O. Klepitskaya, R. Loureiro, D. Magalh ães, J. Rocha, P. Soares-da-Silva Source Type: research