Integrity of Dopaminergic Terminals in the Caudate Nucleus Modulates Rest Tremor in Parkinson ’s Disease

Background: Resting tremor (RT) is a symptom of Parkinson's disease (PD) with an uncertain connection to the dopaminergic (DA) system. In contrast to other motor symptoms in PD, severity of tremor does not show a correlation with loss of striatal dopamine, but dopaminergic denervation of specific parts of the basal ganglia has been inconsistently related to tremor-dominant PD.
Source: Parkinsonism and Related Disorders - Category: Neurology Authors: Source Type: research