Multiple checkpoints ensure ribosomes have the correct end

by Jacob Gordon, Robin E. Stanley

The 3 ′ end of the 18S ribosomal RNA is formed by the endoribonuclease Nob1. How cells ensure the accuracy of the 3′ end has remained a mystery. A new study in PLOS Biology revealed that there are multiple checkpoints to ensure that only ribosomes containing the correct 3′ end participate in transla tion.

The 3’ end of 18S ribosomal RNA is formed by the endoribonuclease Nob1, but how cells ensure the accuracy of the 3’ end has been a mystery. A new study in PLOS Biology has revealed multiple checkpoints that ensure only ribosomes containing the correct 3’ end participate in translation.

Source: PLoS Biology: Archived Table of Contents - April 30, 2024 Category: Biology Authors: Jacob Gordon Source Type: research