Assessing autosomal aneuploidy in ancient genomes

Trends Genet. 2024 Apr 24:S0168-9525(24)00080-5. doi: 10.1016/j.tig.2024.04.006. Online ahead of print.ABSTRACTUsing genetic methods, aneuploidies can be detected in ancient human remains, which is so far the only way to reliably prove their existence in the past. As highlighted in recent studies by Rohrlach et al. and by Anastasiadou et al., this initial step enables a deeper exploration of the history of rare diseases, encompassing the social and historical contexts of the afflicted individuals.PMID:38664113 | DOI:10.1016/j.tig.2024.04.006
Source: Trends in Genetics : TIG - Category: Genetics & Stem Cells Authors: Source Type: research