Anti-inflammatory effect of Trichospira verticillata via suppression of the NLRP3 inflammasome in neutrophilic asthma

This study demonstrates that TVE modulates the binding of NLPR3 to NEK7, thereby reporting novel insights into the mechanism by which TVE inhibits NLRP3 inflammasome. These findings suggest TVE as a potential therapeutic of NLRP3 inflammasome-mediated diseases, particularly NA.PMID:38668995 | PMC:PMC11048967 | DOI:10.1111/jcmm.18356

Source: Molecular Medicine - April 26, 2024 Category: Molecular Biology Authors: Hyeyun Yang Gunwoo Park Sojung Lee Sumin Lee YeJi Kim Nelson A Zamora Dong-Keun Yi Soo-Yong Kim Chun Whan Choi Sangho Choi Yong Hwan Park Source Type: research