Addition of constitutional symptoms to the SLEDAI-2K improves overall disease activity assessment: A pilot study

CONCLUSION: The addition of constitutional symptoms to SLEDAI-2K, particularly fatigue, resulted in a marginal increase in its correlation with PGA, and new constitutional symptoms associated with higher SLED-O and PGA scores. As fatigue is subjective and difficult to attribute to SLE, its validity and inter-rater reliability in scoring remains uncertain. The clinical utility of SLED-R remains unclear, and further studies of its validity and reliability are needed.PMID:38664230 | DOI:10.1177/09612033241249785

Source: Lupus - April 25, 2024 Category: Rheumatology Authors: Erik W Anderson Marissa Sansone Bhakti Shah Myriam Kline Giovanni Franchin Cynthia Aranow Meggan Mackay Source Type: research