Neuroinflammation driven by human immunodeficiency virus-1 (HIV-1) directs the expression of long noncoding RNA RP11-677M14.2 resulting in dysregulation of neurogranin in vivo and in vitro

Neuroinflammation and synaptodendritic damage represent the pathological hallmarks of HIV-1 associated cognitive disorders (HAND). The post-synaptic protein neurogranin (Nrgn) is significantly reduced in the f...

Source: Journal of Neuroinflammation - April 24, 2024 Category: Neurology Authors: Roberta S. dos Reis, Marc C. E. Wagner, Savannah McKenna and Velpandi Ayyavoo Tags: Research Source Type: research