Exploring the mechanism of the reductive amination of acetophenones via the Borch approach: the role of the acid catalyst

Org. Biomol. Chem., 2024, Advance Article DOI: 10.1039/D4OB00160E, PaperJo ão P. A. Souza, Amanda K. Jacobs, Leandro Piovan, Renan B. Campos In the reductive amination process, the acid catalyst plays a crucial role not only in the elimination of water but also in the nucleophilic step, particularly when electron-donating groups are installed at the para-position of the acetophenone. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research