A hospital management algorithm for acute poisoning by Paraquat ® in a pediatric population, a series of cases

We describe a case series of 14 pediatric patients from the department of Cauca, Colombia, with acute intoxication after oral intake of paraquat. Patients were referred to a medium-high complexity hospital in southwestern Colombia and treated according to an institutional protocol for acute paraquat poisoning. Acute paraquat poisoning after oral ingestion is associated with a high mortality rate, even with timely medical attention, as the compound has no known antidote and quickly reaches systemic concentrations for fulminant poisoning. Based on the available literature, our center has proposed a clinical protocol including early standard management, immunosuppressive and antioxidant treatments, and systemic removal techniques. This protocol suggests an adequate approach to acute paraquat poisoning in the pediatric population.PMID:38648344 | DOI:10.7705/biomedica.7024
Source: Biomedica : Revista del Instituto Nacional de Salud - Category: International Medicine & Public Health Authors: Source Type: research