Seronegative patients with primary Sj ögren's syndrome and non-pSS sicca test positive for anti-SSA/Ro52 and -Ro60 in saliva

CONCLUSION: Our findings suggest that salivary anti-SSA/Ro antibodies are potential discriminatory biomarkers for pSS, which may also identify seronegative patients, addressing the unmet clinical need of early detection and stratification of pSS.PMID:38641012 | DOI:10.1016/j.bbadis.2024.167168

Source: Biochimica et Biophysica Acta - April 19, 2024 Category: Biochemistry Authors: Sarah Kamounah Fang Wei Jin Kyun Park Yeong-Wook Song David Chia David T W Wong Anne Marie Lynge Pedersen Source Type: research