Sex, Age, and Species Differences of Perfluorooctanoic Acid Modeled by Flow- versus Permeability-limited Physiologically-Based Pharmacokinetic Models

In conclusion, the permeability PBPK model could interpret age, sex, and species differences and it could improve the accuracy of human prediction.PMID:38642821 | DOI:10.1016/j.tox.2024.153806

Source: Toxicology - April 20, 2024 Category: Toxicology Authors: Go-Wun Choi Dong Wook Kang Ju Hee Kim Seok-Jin Cho Yong-Bok Lee In-Ho Kwon Hea-Young Cho Source Type: research