Identification of ferroptosis-related key genes associated with immune infiltration in sepsis by bioinformatics analysis and in vivo validation

CONCLUSION: MAPK14 and ACSL4 could become robustly reliable and promising biomarkers for sepsis by regulating ferroptosis through the NLRP3 pathway, which is mainly associated with T-cell infiltration.PMID:38649061 | DOI:10.1016/j.gene.2024.148482

Source: Gene - April 22, 2024 Category: Genetics & Stem Cells Authors: Rui Shi Chunyun Bai Shibo Sun Fang Wang Chaozhong Li Chongyu Wang Lidan Hu Ziwen Zhao Qiuzhe Guo Guanhua Du Dan Xu Alex F Chen Weimin Yang Source Type: research