6-O-angeloylplenolin inhibits osteoclastogenesis in vitro via suppressing c-Src/NF- κB/NFATc1 pathways and ameliorates bone resorption in collagen-induced arthritis mouse model

In conclusion, 6-OAP has the potential to be further developed for the treatment of RA-related bone erosion.PMID:38643905 | DOI:10.1016/j.bcp.2024.116230

Source: Biochemical Pharmacology - April 21, 2024 Category: Drugs & Pharmacology Authors: Zhi-Chao Li Min Li Ling-Xiang Xiao Xi Zheng Rong Li Shi-Jia Dong Yue Wang Hong-Yu Wen Kun-Lin Ruan Ke-Guang Cheng Ming Chen Yan-Hui Tan Source Type: research